Repbase Reports |
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| 2007, Volume 7, Issue 4 |
| April 30, 2007 |
| Copyright © 2001-2024 - Genetic Information Research Institute, California |
| ISSN# 1534-830X |
| Page 146 |
IS4EU-2_DR |
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A family of autonomous IS4EU transposons - a consensus. |
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Submitted: 29-Apr-2007 |
Accepted: 01-MAY-2007 |
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Key Words: ISL2EU; DNA transposon; Transposable Element; IS4EU; Interspersed repeat; IS4EU-2_DR |
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Source: Danio rerio |
Organism: Danio rerio |
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio |
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Authors: Kapitonov,V.V. and Jurka,J. |
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Title: IS4EU, a novel superfamily of eukaryotic DNA transposons. |
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Journal: Repbase Reports 7(4), 146-146 (2007) |
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Abstract: DNA transposons from the IS4EU superfamily are characterized by the TA target site duplications. These transposons are wide spread in metazoans, including fish, frogs, lancelet, sea urchins, sea squirts, insects and cnidarians. Autonomous IS4EU transposons encode two proteins: the IS4EU-TR transposase, which is similar to the IS4-like bacterial transposases, and the ISEU-EX DNA exonuclease. Based on the conservation of both proteins in highly divergent transposons, is is clear that they are necessary for transpositions. IS4EU-2_DR is a consensus sequence of a young family of autonomous IS4EU transposons that were active in the zebrafish genome in a last few million years. The IS4EU-2_DR transposon is characterized by 13-bp terminal inverted repeats, TA target site duplications, and it encodes two proteins: (i) the 475-aa transposase, IS4EU-1_DR1p, composed of the THAP DNA-binding domain and catalytic "DDE" domain, which is conserved in all IS4EU transposases, and (ii) the 515-aa IS4EU-1_DR2p exonuclease. Questions and comments send to Vladimir Kapitonov.
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Derived: [1] (Consensus) |
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Download Sequence - Format: IG, EMBL, FASTA |
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References: |
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