Repbase Reports |
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| 2010, Volume 10, Issue 4 |
| April 30, 2010 |
| Copyright © 2001-2024 - Genetic Information Research Institute, California |
| ISSN# 1534-830X |
| Page 645 |
Academ-1_HM |
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This family belongs to the Academ superfamily of DNA transposons. |
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Submitted: 30-Apr-2010 |
Accepted: 30-APR-2010 |
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Key Words: Academ; DNA transposon; Transposable Element; Academ-1_HM |
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Source: Hydra vulgaris |
Organism: Hydra vulgaris |
Taxonomy: Eukaryota; Metazoa; Cnidaria; Hydrozoa; Hydroidolina; Anthoathecata; Aplanulata; Hydridae; Hydra |
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Authors: Kapitonov,V.V. and Jurka,J. |
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Title: Academ - a novel superfamily of eukaryotic DNA transposons. |
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Journal: Repbase Reports 10(4), 645-645 (2010) |
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Abstract: Academ is a novel superfamily of DNA transposons that populate genomes of metazoans, including cnidarians, insects, sea urchins, lancelet, and fish. The autonomous Academ transposons encode a ~1500-aa protein composed of a novel Academ transposase domain, which is not similar to transposases encoded by any other transposable elements reported previously, the XPG domain, and the putative Cys8 zinc finger. The XPG domain is structurally and functionally related to FEN-1; divalent metal ion-dependent exo- and endonuclease, and bacterial and bacteriophage 5'-3' exonucleases. The Cys8 zinc finger is a conserved set of eight cysteines: Cys-X-Cys-X3,4-Cys-X3,10-Cys-X-Cys-X6-Cys-X3-Cys-X1,2-Cys. Academ transposons generate 3-bp target site duplications and contain terminal inverted repeats whose length varies from 6 to 530 bp. Usually, Academ transposons have the 5'-TAG and CTA-3' termini. Academ-1_HM is a young family. The consensus was derived from multiple alignment of several copies >95% identical to it. Imperfect TIRs are 14 bp long.
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Derived: [1] (Consensus) |
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Download Sequence - Format: IG, EMBL, FASTA |
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References: |
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